Question

Do gram positive bacteria form endotoxins? Explain the answer

Answer 1

LPS known as lipoglycans and endotoxin large molecule consisting lipid and Polysacchrides composed of O antigen outer core and inner core joined by covelent bond and found in -Ve bacteria and elict Strong from Immune responce in animals and Human,

Gram positive bacteria are the most common cause of "Sepsis",These toxin include Lipid and polysaccharide that is present in outer membrane gram negative bacterium and several other secreted endotoxins and endotoxin in other bacteria,

While endotoxin are Heat Stable LPS and Protein Complex Structural of Cell wall on -Ve Bacteria and Liberated only cell lysis (or) death of Bacteria,

important Points-:a)Heat tolerate

b)Weakly Immunogenic

c)Toxoid cannot be Made

d)Located on Chromosomal gene and molecular weight 50-1000K Dalton

e)Enzymatic Activities,Ex-:E-Coli,Salmonella Typhi,