Order the following steps in the pyruvate dehydrogenase reaction. The answer is scored as ALL OR NOTHING, so all steps must be in the correct order for credit.
Question 5 options:
a) Pyruvate and thiamine pyrophosphate react form hydroxyethyl-TPP. CO2 is released.
b) The reduced coenzyme bound to PDH is reoxidized using electrons from FAD.
c) An acetyl group is added to a coenzyme bound to PDH, forming acetyl-dihydrolipoamide.
d) The acetyl group is transferred to CoA, forming acetyl-CoA.
e) Electrons from FADH2 are transferred to NAD+ forming NADH and H+.
Answer:
Order the following steps in the pyruvate dehydrogenase reaction.
The correct order is:
a) Pyruvate and thiamine pyrophosphate react to form hydroxyethyl-TPP. CO2 is released.
b) An acetyl group is added to a coenzyme bound to PDH, forming acetyl-dihydrolipoamide.
c) The acetyl group is transferred to CoA, forming acetyl-CoA.
d) The reduced coenzyme bound to PDH is reoxidized using electrons from FAD.
e) Electrons from FADH2 are transferred to NAD+ forming NADH and H+.
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