In a haploid species, a mutation arises in one individual in a population on 1000 individuals. If this mutation is neutral, what is the probability that it will eventually go to fixation?
Question.
Answer.
Let's assume, N = Population size
u = Rate of introduction of a new mutation.
As it is given that the species is diploid.
Hence, Probability of getting a new mutation = 2Nu
Probability of fixation = 1/2N
Rate of fixation of the neutral mutation = Rate of getting a neutral mutation X Probability of fixation.
= 2Nu X 1/2N
= u
Therefore, the rate of fixation for a neutral mutation is simply the rate of introduction of such mutations.
Hence , u = 1/ 1000
= 0.001.
Please feel free to ask if anything is not understood.
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