Question

Why is the incidence of sickle-cell anemia an excellent example of a “balanced polymorphism,” in which...

Why is the incidence of sickle-cell anemia an excellent example of a “balanced polymorphism,” in which two or more alleles are maintained by natural selection in a population?

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Answer #1

Balanced polymorphism is a condition in which the two different versions of a single gene is maintained in a population of an organism because individual carrying both the forms of a gene are able to livee better than those individuals which carries two copies of either version alone.

The evolutionary process which helps the two version of the gene to survive with the passing period of time is known as balancing selection. In other words heterozygote has a selective advantage. Being a heterozygote, sickle cell anemia would gives us a resistance towards malaria. Recessive homozygous would die in early childhood due to sickle cell anemia and dominant homozygotes would die due to malarial infection.

Being a heterozygotes helps us to survive for a little longer so as to produce children and therefore this balancing selection leads to balance polymorphism.

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