Question

An individual with a defective oxidative part of the  Pentose Phosphate Pathway can still produce sufficient levels of NADPH for fatty acid synthesis due to the presence of which of the following enzymes?

A.

Fat acid synthase

B.

Malic enzyme

C.

Acetyl-CoA Carboxylase

D.

Citrate lyase

E.

C9-desaturase

Answer 1

Fat acid synthase helps in the synthesis of fatty acid and utilize NADPH. So option A is wrong.

The malic enzyme converts malate to pyruvate the during the reaction NADPH is synthesized. So option B is correct.

Acetyl-CoA Carboxylase adds CO2 to acetyl Co-A which is then converted to malonyl Co-A. So option C is wrong.

Citrate lyase converts citrate to acetyl Co-A and oxaloacetate. So option D is wrong.

C9-desaturase add a double bond in the saturated fatty acid to make then unsaturated fatty acid. So option E is also wrong.

Hence correct answer is option B. Malic enzyme