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What can the two following phenomena, frequency of recombination between two alleles and the overall frequency...

What can the two following phenomena, frequency of recombination between two alleles and the overall frequency of haplotypes, tell you about the AGE of a mutated allele on a chromosome with another allele. Please explain the connection. (Hint: Think about the age of the CCR5-Δ32 mutation)

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Answer #1

The age of a mutated allele on a chromosome with another allele can be figured out by understanding the recombination frequency between two alleles and overall frequency of haplotypes. One of the examples is the CCR5-Δ32 mutation, which depicts the selective pressure. It depends on the geographical location and distribution which defines its role in playing and conferring genetic polymorphism. The age can be determined by the pressure that is applied for figuring out the frequence.

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