Question

This organism is capable of growing on acetate as a sole source of carbon and energy. An examination of the complete genome sequence reveals an absence of genes with homology to those known to encode fructose-1,6-bisphosphatase and transketolase. Why does this surprise you? What problem would this pose for the cell, and how might this organism be overcoming these apparent deficiencies?

Answer 1

Fructose 1,6 bisphosphatase enzyme involved in gluconeogenesis which leads to synthesis of new glucose, so absence of fructose 1,6 bisphosphatase cause no glucose synthesis.

Transketelose enzyme used in Pentose phosphate snynthesis involved in NADPH synthesis or ribose synthesis.

If this is non functional then NADPH and ribose synthesis won't take place.

To overcome this problem, bacteria uses acetyl coA as carbon source for oxidation via kreb's cycle to release ATP and NADH which further undergo Electron transport chain to release ATP.

This ATP is used for energy for the survival of this bacteria.

Hope it's clear..thanks