Familial hypercholesterolemia is an autosomal dominant trait leading to high cholesterol and often to heart disease. Color blindness is an X-linked recessive trait. Stephanie has high cholesterol and normal color vision. Her mother has high cholesterol and normal vision. Her father is color blind with normal vision. Stephanie’s husband, Joe is colorblind and has normal cholesterol. What proportion of Joe and Stephanie’s sons will be colorblind and have high cholesterol?
Only one son with genotype AaXcY will be colorblind and have high cholesterol.
Proportion of stephanies son who will be colorblind and have high cholesterol= 1/8
= 12.5%
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