Question

#1

I post this twice, please don't duplicate answer I need two different views. Thanks

PLEASE, PLEASE, PLEASE, FOLLOW THE INSTRUCTOR. I DONT NEED JUST SOMETHING, I NEED YOU TO ANSWER WHAT I NEED. PLEASE DONT ANSWER IF YOU CANT DO EXACTLY I NEED. ALSO, PLEASE DO NOT COPY FROM ANY WEBSITE, IT HAS TO BE YOUR OWN WORD.

1. CHOOSE ONE OF TOPIC I LISTED

2.WHY YOU CHOOSE THIS PARTICULAR TOPIC

3. INCLUDE YOUR REPUTABLE SOURCE

4. REFERENCE

week's topic is cancer. Please write a paragraph about any topic that has reference to cancer and please tell me WHY (1 pt) you chose your topic (you must include why you chose your topic to earn full credit). Duplicate topics are acceptable because you will each have your own reasons. As always, please include your reputable source (0.5 pt) to earn full credit.

Although the list is endless, here are some suggestions: PLEASE USE THE TOPIC I PROVIDED ===> LINKS BELLOW

http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted (Targeted Cancer Therapies - scroll down to the bottom of the article to see drugs that have been FDA approved to target different cancers)

http://cancer.sanger.ac.uk/cancergenome/projects/census/ (COSMIC - Catalog of somatic mutations in cancer - this lists information about 522 different cancer genes)

http://www.acgtfoundation.org/ (Alliance for Cancer Gene Therapy)

http://www.biooncology.com/pipeline-molecules  (cancer research pipeline molecules)

http://www.proton-therapy.org/howit.htm and http://www.cancer.net/navigating-cancer-care/how-cancer-treated/radiation-therapy/proton-therapy (proton therapy)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462607/ (Ipilimumab (Yervoy) Prolongs Survival in Advanced Melanoma)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128689/ (Palbociclib: an evidence-based review of its potential in the treatment of breast cancer)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291972/ (miR-3156-3p is downregulated in HPV-positive cervical cancer and performs as a tumor-suppressive miRNA)

https://www.ncbi.nlm.nih.gov/pubmed/28218725 (Treating Cancer by Targeting Telomeres and Telomerase)

https://www.ncbi.nlm.nih.gov/pubmed/28217707 (microRNA regulation of human pancreatic cancer stem cells)

https://www.ncbi.nlm.nih.gov/pubmed/28210556 (Are breast cancer stem cells the key to resolving clinical issues in breast cancer therapy?)

https://www.ncbi.nlm.nih.gov/pubmed/28209166 (Intra-tumor heterogeneity from a cancer stem cell prospective)

https://www.nih.gov/news-events/nih-research-matters/how-elephants-defend-against-cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135649/ (Li-Fraumeni Syndrome)

https://www.cancer.org/latest-news/why-lung-cancer-strikes-nonsmokers.html

https://www.ncbi.nlm.nih.gov/pubmed/27610367 (Uncovering Driver DNA Methylation Events in Nonsmoking Early Stage Lung Adenocarcinoma)

Answer 1

Topic: Targeted Cancer Therapies

Targeted cancer therapies are drugs delivery strategy that arrest the growth as well as metastasis by restricting with particular molecules that are participated in the multiplication, growth and advancement of cancer. Targeted cancer therapies also known as "molecularly targeted drugs".

I have selected this topic because it really contribute a lot in the area of anti-cancer therapy, different strategies are undertaken for upgrading the efficacy of anticancer surrogate have rised over many past decades. These strategies mainly include targeted anticancer delivery of drug strategies. Therefore, it becomes essential to understand this technique. It is assumed that more targeted therapies will advance into regular clinical use in coming future.

References: https://www.sciencedirect.com/science/article/pii/S2542364917300596.