Question

Which class of antibodies would trigger the inflammation associated with the allergic response to egg antigens...

Which class of antibodies would trigger the inflammation associated with the allergic response to egg antigens in the flu vaccine?

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Answer #1

IgE class of immunoglobulin or antibody will trigger the inflammation associated with the allergic response to egg antigens in the flu vaccine. IgE is an antibody is present in small amount in every individual but allergic individuals generally produce IgE in larger quantities. The overproduction of IgE leads to activation of the cells like mast cells and basophils, which contain various mediators, such as histamine. These mediators cause typical allergic symptoms, like localized swelling, inflammation, etc.

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