In complex disorders, the following observation(s) support the presence of genetic risk factors in a patient:
a) early onset of the disease
b) recurrence in several close relatives
c) absence of known environmental risk factors
d) a severe form of a disease with variable expressivity
e) all of the above
Answer:
In complex disorders, the following observation(s) support the presence of genetic risk factors in a patient:
a) early onset of the disease
b) recurrence in several close relatives
c) absence of known environmental risk factors
d) a severe form of a disease with variable expressivity
e) all of the above - Correct Option
Explanation: Early onset of disease indicates a higher influence of genetic effects. Inherited genetic disease in human often have variable expressivity. Recurrence in several close relatives also indicates genetic-factor association of the disease.
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