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The rationale for genome wide association studies (GWAS) based on SNP arrays is that: a) susceptibility...

The rationale for genome wide association studies (GWAS) based on SNP arrays is that:

a) susceptibility to common disorders can be due to rare variants

b) common disorders always have a genetic basis

c) common disorders are caused by both genetic and environmental risk factors

d) common disorders are complex genetic disorders

e) susceptibility to common disorders can be due to common variants

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Answer #1

Answer : e.

The rationale for genome wide association studies (GWAS) based on SNP arrays is that : Susceptibilty tocommon disorders can be due to commmon variants. It is an observational study of a genome wide set of genetic variants in different individuals to see if any variant is associated with a trait. GWASs typically focus on associations between single nucleotide polymorphisms and traits like major human diseases, but can equallybe applied to any other organism.

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