Question

Cystic fibrosis is one of the most common autosomal recessive disorders. The carrier frequency in a general population is 1/25. A woman who knows she is heterozygous for the mutation that causes cystic fibrosis (CF) marries a man with no family history of CF at all. What is the probability that they will produce a child that has cystic fibrosis?

Suppose the couple above has a child with cystic fibrosis. What is the chance that their second child will have it? Remember to explain why.

Answer #1

The autosomal recessive disorder makes it 25% probability for the child to get the disease or carry the genes for CF. With each pregnancy, the child may or may not be affected by the disease as only the mother is heterozygote for it. The chances that the child will be produced with CF or cystic Fibrosis is around 25%. It is the carrier frequency.

Now lets us say the couple already have a child with cystic Fibrosis. The chances of the second child to have the disease also remain same because it depends on what genes are being inherited to the child. The child might get the gene for CF and it might be recessive or dominant. If it is recessive, the child do not suffer from the disease but carry the gene for it. If the child is dominant, the child carry the gene and also suffers from the disease.

Cystic fibrosis is one of the most common autosomal recessive
disorders. The carrier frequency in a general population is 1/25. A
woman who knows she is heterozygous for the mutation that causes
cystic fibrosis (CF) marries a man with no family history of CF at
all. What is the probability that they will produce a child that
has cystic fibrosis? Suppose the couple above has a child with
cystic fibrosis. What is the chance that their second child will
have...

Attached earlobe and cystic fibrosis are both autosomal
recessive traits. A woman with attached earlobes, that is a carrier
of cystic fibrosis, marries a man that is genotypically normal for
cystic fibrosis and is a carrier of the attached earlobe trait.
What is the probability that they will have a child with
non-attached earlobes that is a carrier of cystic fibrosis?
A- 1/4
B-1/16
C-1/2
D-3/4

Cystic fibrosis is an autosomal recessive disorder. Beth and Tom
do not have cystic fibrosis but each have a sibling with cystic
fibrosis. Beth's parents and Tom's mother do not have the disease.,
but Tom's father does. Calculate the probability that if this
couple has a child, the child will NOT have cystic fibrosis.

A phenotypically normal couple has had one normal child and a
child with cystic fibrosis, an autosomal recessive
disease. The incidence of cystic fibrosis in the
population from which this couple came is 1/500. If
their normal child eventually marries a phenotypically normal
person from the same population, what is the risk that the
newlyweds will produce a child with cystic fibrosis?

The Autosomal Recessive disease, Cystic Fibrosis (CF),
runs in Jill’s family. Jill is unaffected. Based on this data,
select which of the following statements could be True?
A.
If Jill’s Paternal Aunt is affected and her Paternal
Grandparents are unaffected. There is a 2/3 probability her father
is a Carrier
B.
In the future, Jill’s parents have another child and
that child has CF. Therefore, her parents have a 100% probability
of being Carriers
C.
Jill could never produce a...

The Autosomal Recessive disease, Cystic Fibrosis (CF), runs in
Jill’s family. Jill is unaffected. Based on this data, select which
of the following statements could be True?
A.
If Jill’s Paternal Aunt is affected and her Paternal
Grandparents are unaffected. There is a 2/3 probability her father
is a Carrier
B.
In the future, Jill’s parents have another child and that child
has CF. Therefore, her parents have a 100% probability of being
Carriers
C.
Jill could never produce a...

Among U.S. Caucasians, the frequency of the CF- allele causing
the recessive autosomal disease cystic fibrosis is 0.02. What is
the Δq for the CF allele after one generation of random
mating and selection?

Cystic fibrosis (CF) is caused by a recessive allele. A couple
who do not have CF have a child that has CF. What is the
probability that if they have another child, that the child will be
heterozygous for CF?
1/2 or 50%
1/4 or 25%
3/4 or 75%
0%

Question 5
Cystic fibrosis (CF) is a recessive gene disease meaning that a
child has to inherit a defective CF gene from each parent. This
means that there is a 25% chance of a child having cystic fibrosis
if both parents are CF carriers Hence the number of children with
CF (in a family whose parents are CF carriers) has a binomial
distribution with n = the number of children in the family and p=
0.25
i. In a family...

Question 5
Cystic fibrosis (CF) is a recessive gene disease meaning that a
child has to inherit a defective CF gene from each parent. This
means that there is a 25% chance of a child having cystic fibrosis
if both parents are CF carriers Hence the number of children with
CF (in a family whose parents are CF carriers) has a binomial
distribution with n = the number of children in the family and p=
0.25
i. In a family...

ADVERTISEMENT

Get Answers For Free

Most questions answered within 1 hours.

ADVERTISEMENT

asked 12 minutes ago

asked 27 minutes ago

asked 29 minutes ago

asked 29 minutes ago

asked 38 minutes ago

asked 38 minutes ago

asked 43 minutes ago

asked 45 minutes ago

asked 46 minutes ago

asked 46 minutes ago

asked 48 minutes ago

asked 1 hour ago