3.
Four molecules of _____ proteins together form a homotetramer, also known as a repressor.
lacZ |
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lacY |
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lacI |
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lacA |
Lac operon is an inducible operon that can be negatively regulated by Lac repressor or positively regulated by cAMP system.
Lac I,the Lac repressor protein binds to the operator through two of it's subunit and prevent RNA polymerase from binding to the promoter region and hence prevent Transcription. Lac repressor is a homotetramer consisting of two dimer subunits that bind to DNA.The DNA binding site is present at the N terminal and a tetramerization region is present at the C terminal.The DNA binding domain has helix turn helix motif.
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