Question

which treatment induces thynine dimers that may inhibit dna replication and transcription?

- exposure to a solution of 70% isopropanol

-exposure to ultraviolet radiation

-exposure to pressures greater than 1000 psi

-exposure to temp of 200 degrees C

Answer 1

DNA exposed to ultraviolet (UV) induces the thymine dimer formation. The double bonds present in the thymine absorbs energy from the UV light and opens up. so that they can react to the nearby nitrogeneous base present in the DNA. If there is presence of two consecutive thymine then they can reacts among themselves and form dimer. This dimer formation interfere with the movement of DNA polymerase on the DNA during DNA replication.