Below are 6 steps involved in the evolution of Ab resistance,
listed in a scrambled order. Organize the steps in the order in
which they actually occur
1. An advantageous mutation occurs that does not influence Ab-resistance, but increases growth rate.
2. Antibiotics are introduced into the environment.
3. A deleterious mutation occurs in a single cell that confers antibiotic resistance but compromises growth rate.
4. The individual cell with the Ab-resistant allele survives and reproduces slowly.
5. The antibiotic is more-or-less obsolete (useless, ineffective).
6. Selection favors compensatory mutations in the Ab-resistant population to favor the evolution of higher growth rates.
1. Antibiotics are introduced into the environment.
2. A deleterious mutation occurs in a single cell that confers antibiotic resistance but compromises growth rate.
3. The individual cell with the Ab-resistant allele survives and reproduces slowly.
4. An advantageous mutation occurs that does not influence Ab-resistance but increases growth rate.
5. Selection favors compensatory mutations in the Ab-resistant population to favor the evolution of higher growth rates.
6. The antibiotic is more-or-less obsolete (useless, ineffective).
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