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Human ABO blood type is determined by three alleles
(IA, IB, and i)
whose gene products modify the H antigen produced by protein
activity of an independently assorting H gene. A rare abnormality
known as the “Bombay phenotype” is the result of epistatic
interaction between the gene for the ABO blood group and the H
gene. Individuals with the Bombay phenotype appear to have blood
type O based on the inability of both anti-A antibody and anti-B
antibody to detect an antigen. The apparent blood type O in Bombay
phenotype is due to the absence of H antigen as a result of
homozygous recessive mutations of the H gene. Individuals
with the Bombay phenotype have the hh genotype. Use the
information above to make predictions about the outcome of the
cross shown below: IAI B
Hh×IAIB Hh
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Part A
For this cross, what fraction will have type O blood?
Express your answer as a fraction. Example: 1/8
For this cross, will have type O blood.
Part B
For this cross, what fraction will have type A blood?
Express your answer as a fraction. Example: 1/8
For this cross, will have type A blood.
SubmitRequest Answer
Part C
For this cross, what fraction will have type AB blood?
Express your answer as a fraction. Example: 1/8
For this cross, will have type AB blood.
SubmitRequest Answer
Part D
For this cross, what fraction will have type B blood?
Express your answer as a fraction. Example: 1/8
For this cross, will have type B blood.
SubmitRequest Answer
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