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Herpes simplex virus is an enveloped, icosahedral virus. This virus can be inactivated easily by heat,...

Herpes simplex virus is an enveloped, icosahedral virus. This virus can be inactivated easily by heat, alcohols, or by ultra violet (UV) radiation.

Of these methods, which one is most likely to prevent virus eclipse, and which one is most likely to allow it to occur? Explain your answer fully.

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Answer #1

inactivation by alcohol is a best mathod for enveloped HSV. because alcohol or detergent react readily with surface protein and distroy it within a 10 to 15 minutes. where is prolonged heating process is required for HPV enveloped. it required 24hrs to 48hrs for completely deactivation of virus. also in addition depending upon the load of virus the time may varies (it may increase). however heating process is still good as compared to UV irradiation. UV irradiation directly affects replication of virus. it distroys the DNA inside capsule but it depends on UV light intensity and envelope of virus. it required prolonged time depending upon the envelope size and UV radiation dose. some time it fails to inactivated.

hence alcohol inactivation is best and UV irradiation method is less acceptable.

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