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Immunity: 1. Which defenses protect us from infection of P. aeruginosa? 2. Does P. aeruginosa induce...

Immunity:

1. Which defenses protect us from infection of P. aeruginosa?

2. Does P. aeruginosa induce a specific type of immune response (example: delayed-type hypersensitivity)? If so, which one(s)?

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Answer #1

1. The host defenses are majorly phagocytic against P. Aeruginosa. The primary response may be non specific and may later antibodies maybe produced against LPS and later to even more specific antibody response which may opsonize the bacteria through the complimentary binding and initiate the antibody mediated bactericidal effect.

2. Yes the response is majorly humoral instead of cell-mediated as evident from a intense infection in patients unable to mount an appropriate immune response.

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