In a population where hair color gene can be determined by 4 alleles B(brown)=0.210654 , b(blonde) =0.319212, g(black) =0.206791, e(red) =0.216791. The gene for hair texture can be determined by 3 alleles C(curly)=0.225879 c=(not curly)=0.412122 w(wavy)=0.345621. The gene for hair porosity can be determined by 2 alleles T(thin)=0.456123 and u(coarse)= 0.515123. Assume Hardy-Weinberg equlibrium, what is the frequency of getting Black, wavy, thin hair? (p2 + 2pq + q2 + 2pr + 2qr + r2 = 1). ?
According to hardy - weinberg equilibrium
As allele for black and wavy hair is reccesive therefore only possible genotype for wavy and thin hair are gg, ww respectively
frequency for black hair = f(gg) =g^2=(0.206791)^2=0.0427625177
frequency for wavy hair = f(ww)= w^2=(0.345621)^2=0.1194538756
But allel for thin hair is dominant therefore possible genotype for thin hair are TT and Tu
which implies total frequency for thin hair = f(TT)+ f(Tu)= p^2+2pq = 0.208048191+0.469918896 = 0.677967087
now in probablity we have learnt that in case of more than one different events probabilty for them to occur together is calculated by adding indiviual probabilty.
hence frequency for black wavy thin hair is f(gg) + f(ww) + f(TT)+ f(Tu)
i.e, 0.0427625177+0.1194538756+ 0.677967087=0.8401834803
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