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what would happen to the charge across the cell membrane outside cell potassium concentrations are greatly...

what would happen to the charge across the cell membrane outside cell potassium concentrations are greatly increased by KCL injection into the blood

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What would happen to the charge across the cell membrane when outside cell potassium concentrations are greatly increased by KCl injection into the blood:

  • Injection of KCl will increase the extracellular concentration of potassium and it acts as a membrane depolarizing agent.
  • In depolarization, the membrane potential changes from negatively charged to positively charged.
  • Increase in extracellular K+ concentration (hyperkalemia) leads to a decrease in resting potential, causes membrane depolarization and inactivates various voltage gated sodium channels.
  • Due to this, drugs (example KCl injection) have been used as euthanesia agents.
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