Question

Find diseases caused by missassembly or folding of proteins and write amyloid

Answer 1

Diseases caused by protein misfolding and aggregation:

1. Alzeimers disease,

2. Parkinson's disease

3. Huntington disease

4. Creutzfeldt Jakob disease

5. Cystic fibrosis

6. Goucher's disease

7. Amyloidosis

8. Prion diseases

9. Mad cow disease

10. TSE disease

Amyloids: these are aggregates of proteins that become folded into a shape that allows many copies of that protein to stick together forming fibrils. In humanshumans, amyloids are linked to the development of many diseases.

Pathogenic amyloids are formed when previously healthy proteins lose their normal physiological functions and form fibrous deposits in plaques around the cells which can disrupt healthy functions of tissues and organs.