Question

Which of the following is correct about DNA replication? A. Replication begins from one end of...

Which of the following is correct about DNA replication? A. Replication begins from one end of the molecule, and ends at the other end. B. A type of RNA polymerase is the enzyme that lays down the first nucleotide of the daughter strand. C. Replication occurs in one chromosome at a time. D. DNA polymerase III and the primase have opposite directions of functions. E. At the end of replication, two DNA molecules are present- the original molecule, and a newly synthesized DNA molecule.

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Answer #1

Option B is correct.

Explanation:

Replication is bidirectional.

Replication occurs at multiple locations in all the chromosomes simultaneously.

All the polymerases (DNA or RNA) have only 5' ---> 3' polymerase property. No polymerase is found with a 3' ---> 5' polymerase function.

DNA replication is semiconservative. So, both the daughter molecules contain a parent strand at the end of replication.

Primase is required for DNA replication as DNA polymerase can only extend an existing stand but can not initiate strand synthesis de novo. Primase is a DNA dependent RNA polymerase that synthesizes RNA primers on DNA template for the initiation of DNA replication.

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