Question

What is the expected proportion of progeny with recombinant genotypes at the C and E genes...

What is the expected proportion of progeny with recombinant genotypes at the C and E genes from a female who has the following karyotypes (the genetic distance between all adjacent loci is 20cM): a) A-B-C-D-E/a-b-c-d-e B) A-E-D-C-B/a-b-c-d-e C) A-E-D-C-B/a-e-d-c-b

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Answer #1

a) A-B-C-D-E/a-b-c-d-e The genetic distance between C and E is 40cM. Recombinant genotypes (Ce and cE) will occur at a frequency of 40%.

b) A-E-D-C-B/a-b-c-d-e this individual is heterozygous for an inversion spanning B-C-D-E. Any crossover between C and E will result in unbalanced gametes, so 0% recombinant genotypes will occur.

c) A-E-D-C-B/a-e-d-c-b The genetic distance between C and E is 40cM. Recombinant genotypes (Ce and cE) will occur at a frequency of 40%.

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