Question

how a defect in apoptosis will affect the response to anticancer therapies.

how a defect in apoptosis will affect the response to anticancer therapies.

Homework Answers

Answer #1

Apoptosis ,also known as programmed cell death is a normal physiological and biochemical process that takes place in multicellular organism during which each cell undergoes changes and dies so that new cells are formed in its place to maintain a balance.Defects in apoptosis results in uncontrolled cell division and proliferation that leads to cancer.Oncogenic mutations are known to disrupt apoptosis and same mutations go on to reduce the treatment sensitivity of the anticancer therapies.A link between disruption of apoptosis during tumor development to de novo resistance and acquired drug resistance has been established from the studies on c-Myc-induced lymphomagenesis.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
I've been reading how some bacteria will inhibit apoptosis and induce necrosis to inhibit immune response...
I've been reading how some bacteria will inhibit apoptosis and induce necrosis to inhibit immune response but either way the cell dies so why is one helpful to the bacterium but not the other?? How does preventing apoptosis inhibit immune response?
For the chloroplast, explain how a defect in the structure would affect the function, and the...
For the chloroplast, explain how a defect in the structure would affect the function, and the overall health of the cell.
For the mitochondria, explain how a defect in the structure would affect the function, and the...
For the mitochondria, explain how a defect in the structure would affect the function, and the overall health of the cell.
BIOCHEMISTRY: How might a defect in a pancreatic β-cell calcium channel affect insulin release when blood...
BIOCHEMISTRY: How might a defect in a pancreatic β-cell calcium channel affect insulin release when blood glucose levels rise?
Suppose that the market demand for physical therapies is given by the equation P=100-Q. The cost...
Suppose that the market demand for physical therapies is given by the equation P=100-Q. The cost of each therapy is 40. a. What is the socially optimal number of physical therapies? (2 points) b. Suppose that the price of physical therapies is 40. Suppose further that patients have insurance that pays for 50% of the price of physical therapies. How many physical therapies will be purchased? What is the amount of deadweight loss from insurance moral hazard? (4 points) c....
A scientist wants to test how therapies A and B improve the eyesight of rats. She...
A scientist wants to test how therapies A and B improve the eyesight of rats. She has 20 rats to use, but their vision is different, which might affect how much vision they improve. The scientist decides to group the four rats with the worst vision in one group, the next four rats with second-to-worst vision in another group, etc., until the final group has the best vision. Then, from each group she randomly selects two rats to receive therapy...
Define pleiotropy – how does this affect the response to selection acting on alleles, particularly in...
Define pleiotropy – how does this affect the response to selection acting on alleles, particularly in antagonistic pleiotropy?
How would cognitive therapists approach the treatment of depression? How might they criticize humanistic therapies?
How would cognitive therapists approach the treatment of depression? How might they criticize humanistic therapies?
How would over expression of protein phosphatase 1 affect the induction of cAMP-inducible genes in response...
How would over expression of protein phosphatase 1 affect the induction of cAMP-inducible genes in response to hormone stimulation of target cells? Would protein phosphatase 1 affect the function of cAMP-gated ion channels? Why or why not?  
Describe the genetic defect responsible for sickle cell disease. How does this defect cause the symptoms...
Describe the genetic defect responsible for sickle cell disease. How does this defect cause the symptoms of the disease? While there is currently no cure, describe an experimental approach that researchers are currently developing to cure patients.