Question

Part 2: Identify one or more review articles (or primary literature articles) about your cell part.

You may use either PubMed, Google Scholar, Science Direct, and/or Web of Knowledge.

If you have trouble finding articles about your cell part, be sure that you search using multiple different search terms and in multiple different places. For example if you were assigned Nucleus you might search for “Nucleus”, “Nuclear trafficking”, “Nuclear Lamina”, “Nuclear Pore complex” etc.

When using PubMed, be sure to check ‘review’ on the left to search for review articles at first. For other databases try typing "review" in the search bar. After you are familiar with the current state of the field you can check out some primary literature articles (non-review articles).

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*If you are off-campus, make sure to login through CU Boulder library to get free access to articles.

1.Using review and primary literature articles try to answer the questions you posed above (in part1 question2). What things did you learn in your research that you didn’t know before?

  

2. What is still unknown about your cell part? In other words, what questions are scientists still trying to answer about it?

3. How does your cell part relate to human or wildlife disease?

4.List your scientific primary and review journal article(s) that you used for your answers here (Include the Last name of Authors, Title of article, Journal it was published in, and the year it was published- don't worry about formatting your references)

Answer 1

A nucleus differentiates eukaryotic from prokaryotic cells and is the seat of DNA replication, transcription, and RNA processing.  The nuclear envelope surrounding it allows gene expression to be uniquely regulated in eukaryotes. The envelope controls the access of protein to the nucleus and help regulated post transcriptional modification. Also, bidirectional traffic takes place between the cytosol and the nucleus. There are many protein which function in nucleus namely histones, DNA and RNA polymerases, gene regulatory proteins, and RNA-processing proteins which are imported into the nuclear compartment from the cytosol.