Question

TRUE or FALSE (Explain)

The length and sequence of introns dictate the efficiency of the splicing reaction.

Splicing is dictated by sequence features in pre-mRNA transcripts.

Answer 1

Answer:

1) The length and sequence of introns dictate the efficiency of the splicing reaction - Correct (In Drosophila melanogaster larger introns can be spliced efficiently through a process known as recursive splicing which is evolutionarily conserved. In this case, intron length along with recursive sites play an important role in determining the intron efficiency)

2) Splicing is dictated by sequence features in pre-mRNA transcripts - Correct (Splicing is regulated by trans-acting proteins and cis-acting splicing sequences in primary transcripts on the pre-mRNA. Trans-acting proteins include repressors and activators wheras cis-acting splicing sequences include silencers and enhancers.