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The mucosal immune system features a unique environment to minimize inflammation although the mucosal tissue is...

The mucosal immune system features a unique environment to minimize inflammation although the mucosal tissue is under continuous exposure to foreign substances/entities. Explain how this is achieved and why maintaining such condition is beneficial for the body.
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Mucosal tissues harness the microbiota (highly diverse and evolving microbes), it help in the training and function of the immune system of the host. This is how immune system evolve and with time develop the symbiotic relationship. This help in developing the tolerance for innocuous antigens. This all is not a one day phenomenon but starts in the neonate stage. Early exposure develop the strong immune system.

Our mucosal immune system have developed the mucosal firewall to combat the inflammation. This is possible when there will be minimum contact between the microbs and epithelial cells. This is achevied by the mucus secreted by the epethelial cells, antimicrobial peptides and IgA.

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