Question

A mutation in prokaryotic DNA in the sequence encoding the Shine-Dalgarno site may result in which...

A mutation in prokaryotic DNA in the sequence encoding the Shine-Dalgarno site may result in which of the following?

  1. Reduced initiation of translation
  2. Reduced transcription of the mRNA for the gene in which the mutation occurs
  3. Paused ribosomes during elongation
  4. All of the above
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Homework Answers

Answer #1

Answer: Reduced initiation of translation

Explanation:

Shine-Dalgarno (SD) sequence is defined as ribosomal binding site in prokaryotic mRNA.

It helps in initiation of protein synthesis by pairing the ribosome with start codon. Therefore, it helps the ribosome know where to start translation.

Shine–Dalgarno sequence is located on the 30S subunit of mRNA over the start codon.

If mutation occurs in prokaryotic DNA in the sequence encoding the Shine-Dalgarno site then it may affect the initiation of translation (protein synthesis).


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