Question

1)Describe two different ways that a GABA receptor could depolarize the postsynaptic cell.

2)Define voltage clamping. In voltage clamping experiment, it was determined that there is an early and late current. What ion is associated with each of these currents and what direction does it move in?

3)What is the target of tetanus toxin and botoulinium toxin? Why does one produce a rigid paralysis and the other a flaccid paralysis?

Sarin blocks the effects of acetylcholinestrase . 4)How would this effect the :-

a)Ach levels in the synaptic cleft

b)Ach levels in the presynaptic terminal

c)Ach levels in the postsynaptic terminal

Answer 1