Question

Calculate the charge of each ionisable group as well as the net charge of the peptide...

Calculate the charge of each ionisable group as well as the net charge of the peptide below:

His-Trp-Tyr-Asn-Ala-Glu

  1. At pH 6.0?
  2. At pH 8.0?

Given the pKa for some amino acid side chains are:

Histidine = 6.0, Aspartate = 3.9, Glutamate = 4.0, Lysine = 10.5, Arginine = 12

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Homework Answers

Answer #1

Charge of the peptide at the given PH__

At the PH -6 = -1

At the PH - 8 = -1

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