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If you want to use CRISPR to edit a gene to make it resistant to a...

If you want to use CRISPR to edit a gene to make it resistant to a virus, would one round of CRISPR be enough to completely change how the protein encoded by this gene, reacts to the virus? Wouldn't it be useless if we only edit the genome of one cell within an organism, as the organism would produce new cells without the edited gene?

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Answer #1

Yes we can edit a gene in such a way that protein of interest to be produced that fights with virus or that confer resistance to the virue

If we are doing CRISPR editing in whole organism, we can edit the cells which proliferate actively that fights against virus. For example bonemarrow progenitor cells that gives rise to blood cell types participates in immune resistance to the virus. So if we edit the bone marrow cells in whole organism ,it will be useful.

If we are creating a whole organism with modified protein to fight against virus, embryonic stem cells can be modified that results in transgenic edited whole organism birth that confer resistance to the virus

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