Question

The majority of human genes undergo alternative splicing. What benefits are there to alternative splicing?

The majority of human genes undergo alternative splicing. What benefits are there to alternative splicing?

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Answer #1

Alternative splicing : It is a way to generate different mRNA from a primary transcript. It is a regulatory process that results in a single gene coding for multiple proteins.

For eg. The mammalian muscle protein Troponin T gene is spliced in two different ways ie. alpha Troponin T and Beta Troponin T.

Atleast 90% of human gene undergoes alternative splicing. Also, alternating splicing helps in generating transcriptome diversity and provides an opportunity for gene regulation. It generates mRNA encoding proteins with different even opposite functions.

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