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Using an example from the literature explain how either transition state analogs or active stie modifiers...

Using an example from the literature explain how either transition state analogs or active stie modifiers (molecules that can be covalently linked to the active site) can be used to inhibit enzyme function. Describe why this approach would result in an effect similar to what would be observed if one of the catalytic amino acids in the active site were to be modified using a loss of function mutation.

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