Question

A patient presents active rheumatoid arthritis and complains symptoms of malaise, stiffness, and low-

grade fever. The proteins or cytokines most likely causing these symptoms are:

1. IL-4 and IL-10

2. Rheumatoid factor

3. Gamma globulin

4. TNF and IL-1

Answer 1

Rheumatoid factor

• Rheumatoid factor is a protein produced by our immune system that will attack the organisms own tissues.
• it is also an antibody
• due to the high level of Rheumatoid factor in the blood that causes autoimmune diseases, such as rheumatoid arthritis
• rheumatoid arthritis causes joint pain and damages our body.
• common rheumatoid arthritis symptoms are fever and stiffness it occurs regularly in adults
• Some people that as Rheumatoid factor causes low-grade fevers frequently,
• malaise and depression will occur with other symptoms for even weeks or months on ongoing diseases