Question

The primary resident inflammatory cells in the brain are known as:

Select one:

a. Astrocytes and microglia.

b. Astrocytes and neurons.

c. Schwann cells and neurons.

d. T cells and B cells.

e. Oligodendrocytes and microglia

Answer 1

Answer - option A- astrocytes and microglia.

Microglia are macrophages in the CNS. During inflammation microglial cells get activated and produce mediators of inflammation like proinflammatory mediators and antinflammatory mediators such as various interleukines and TNFs , stimulate immune response and clear debris via phagocytosis. Astrocytes are the major cells in CNS and are glial cells ,regulate immune responses in the brain , regulates neurovascular dynamics.

Both microglia and astrocytes are glial cells which support the neuronal network and conduction system.

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