Question

Severe combined immunodeficiency:

1. Individuals with SCID are susceptible to every type of microbial infection

2. Vaccination with live attenuated live virus are proven fatal among infants with SCID

3. Immunodeficiency with decreased or dysfunctional B and T cells

4. Inappropriate development of stem cells

5. All of these

Answer 1

Answer- Severe combined immuno deficiency  is a group of rare congenital syndromes with little or no immune responses. This results in frequent recurring infections with bacteria, fungi, and viruses. . Patients with SCID have a genetic defect that affects T cells and at least one other type(B, and/or NK cells), are defective of immune cell.They have inappropriate development of stem cells due to which less hematopoetic stem cells are formed and results in decreased immunity.they have no immunity so vaccintion of live attenuated virus can be faatal among infants with SCID.

Hence all the options are correct.