Compounds with negative Log p ratios are
equally likely to be reabsorbed efficiently into
the blood stream from the renal tubules as compared to those with
negative Log P ratios.
here comparison is with negative log p ratios to same negative logp
ratios so it is equally like to be reabsorbed.
The logP value is a constant defined as
LogP = log10 (Partition Coefficient) Partition Coefficient,
P = [organic]/[aqueous]
where [ ] indicates the concentration of solute in the organic and aqueous partition.
A negative value for logP means the compound has a higher affinity for the aqueous phase (it is more hydrophilic); when logP = 0 the compound is equally partitioned between the lipid and aqueous phases; a positive value for logP denotes a higher concentration in the lipid phase (i.e., the compound is more lipophilic).
Get Answers For Free
Most questions answered within 1 hours.