Question

# Consider the following allele frequencies for three SNPs SNP1 SNP2 SNP3 Africa A:20%,T:80% G:70%,T:30% C:20%,A:80% Asia...

Consider the following allele frequencies for three SNPs

 SNP1 SNP2 SNP3 Africa A:20%,T:80% G:70%,T:30% C:20%,A:80% Asia A:50%,T:50% G:20%,T:80% C:20%,A:80% South America A:60%,T:40% G:80%,T:20% C:70%,A:30%

Where is this person from?

1) SNP1:A,T

2) SNP2:T,T

3) SNP3: A,A

Can someone please help me? Explaining all the steps. I don't know what to do. Thank you!

The person is from Africa. The logic goes as :

1. SNP1:A,T - 50:50 is ruled out because equal. From remaining 20:80 and 60:40, the difference in minor and major allele is more in 20:80. So, Africa origin. (In SNP allele frequency, the allele with low frequency is minor and that with high frequency is major allele).

2. SNP2:T,T - no conclusion can be drawn because SNP is for G,T.

3. SNP3:A,A - no conclusion can be drawn because SNP is for C,A.

So, the person is from Africa.

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