Question

1. Define human foreskin fibroblasts (HFFs). What are they used for?

2. Define hours post-infection (HPI)

Answer 1

1. Foreskin fibroblast-like stromal cells (FDSCs) also known as Human foreskin Fibroblasts (HFFs) are progenitors isolated from human tissue that are able to differentiate into various cell types.
Human foreskin fibroblasts (hFFs) are used as feeder cells to support the derivation and undifferentiated growth of hESCs (human embryonic stem cells) and are commercially available through the American Type Culture Collection (ATCC).

2. HPI is the no. of hours after which a soecimen is observed once exposed to some sort of infection.