Question

Describe the difference between the replication of the leading and the lagging strand of DNA in E. coli.

Answer 1

The difference between the replication of the leading and the lagging strand of DNA in E. coli is described as follows -

Replication of the leading strand	Replication of the lagging strand
Replication of the leading strand is continuos.	Replication of the lagging strand is discontinuous.
No formation of okazaki fragments involved.	Since the replication is discontinuous, the new DNA strand is formed in form of small segments which are joined together later. These segments/fragments of new DNA are termed as Okazaki Fragments.