Question

Which of the following is TRUE for GPCR signalling? Select all that are true. Select one...

Which of the following is TRUE for GPCR signalling? Select all that are true.

Select one or more:

a. GPCRs can form ion channels in some cases

b. GPCR acts as a GAP

c. signalling is the result of rearrangment of the transmembrane regions of the GPCR

d. Both the GPCR and the G protein can act as downstream signalling molecules

e. G protein acts as a GEF

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Answer #1

Ans.

(c) singnalling is the result of rearrangement of the transmembrane regions of the GPCR

(d) both the GPCR and the G protein can act as downstream signalling molecules.

Explanation: GPRS ( G protein-coupled receptor) undergo confirmation change on perception of extracelluar signal, it transfers the signals through downstream signalling pathways inside the cell. G proteins are membrane bound protein involved in signal transduction from outside of the cell.

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