One of the characteristic property of enzymes is that they work within a specific temperature and pH range. Temperature and pH below or above the range drastically affects the enzyme function due to the denaturation of the enzyme. Therefore it is important for the cell to maintain appropriate temperatures and pH to ensure all the enzymes (whether related to respiration or any other biochemical activity) are fully functional.
if one or more of the enzymes are not functiional, The overall biochemical process will come to halt as the respiratory metabolic pathway will get disrupted at that specific point where enzyme is non-functional. It will have an effect on the overall process of respiration.The biochemical process will not proceed beyond the point and hence the respiration will not accomplish.
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