Question

What does F(ST) tell us about a population? Be specific. Give examples if necessary.

Answer 1

F(ST) stands for- fixation index, is a measure of population differentiation due the genetic structure in that population.

F(ST) estimated from genetic polymorphism, like single nucleotide polymorphisms (SNP ) or microsatellites. Fst value strongly depends on the population choices.

Example- there are following steps for Fst calculation:-

1. Calculate the alleles frequencies

2. Calculate expected genotypic counts

3. Calculate local observed heterozygosities

4. Calculate the local expected heterozygosities

5. Calculate local inbreeding coefficient of each subpopulation

6. Calculate frequency of allele A and then a.

7. Etc