Question

Insertion/deletion (indel) mutations typically cause frameshift mutations. a. What is meant by a frameshift mutation? b....

Insertion/deletion (indel) mutations typically cause frameshift mutations.

a. What is meant by a frameshift mutation?
b. Describe two situations in which an indel mutation would not be expected to cause a frameshift.
c. How could an indel mutation arise spontaneously?
d. Name a disease resulting from insertions (hint: think about diseases that result form the process you identified in part c.

Homework Answers

Answer #1

Answer a.
Frameshit mutations are insertion/deletion mutations wherein the addition or removal of a nucleotide causes the codon framework to change. Now the reading of 3 occurs in a different frame.

Answer b.
Indels in the non-coding regions of the genome.
Indels in the regulatory regions of the genome.

Answer c.
Errors in (or during) DNA replication can cause the spontaneous insertion of deletion of one nucleotide.

Answer d.
Tay-Sachs disease (A 4-base insertion in the hexA gene)

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Experiment 3: The Importance of Cell Cycle Control Some environmental factors can cause genetic mutations that...
Experiment 3: The Importance of Cell Cycle Control Some environmental factors can cause genetic mutations that result in a lack of proper cell cycle control (mitosis). When this happens, the possibility for uncontrolled cell growth occurs. In some instances, uncontrolled growth can lead to tumors, which are often associated with cancer, or other biological diseases. In this experiment, you will review some of the karyotypic differences that can be observed when comparing normal, controlled cell growth and abnormal, uncontrolled cell...
Assignment: What are the main arguments in the article? Please answer within 5 hours. It is...
Assignment: What are the main arguments in the article? Please answer within 5 hours. It is extremely urgent!!!!!!!!!!!!!!!!!!!!!!!! --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- BIOETHICS. Bioethics as a field is relatively new, emerging only in the late 1960s, though many of the questions it addresses are as old as medicine itself. When Hippocrates wrote his now famous dictum Primum non nocere (First, do no harm), he was grappling with one of the core issues still facing human medicine, namely, the role and duty of the...
What topics are covered in the following article? Please answer within 5 hours. It is extremely...
What topics are covered in the following article? Please answer within 5 hours. It is extremely urgent!!!!!!!!!!!!!!!!!!!!!!!! --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- BIOETHICS. Bioethics as a field is relatively new, emerging only in the late 1960s, though many of the questions it addresses are as old as medicine itself. When Hippocrates wrote his now famous dictum Primum non nocere (First, do no harm), he was grappling with one of the core issues still facing human medicine, namely, the role and duty of the physician....
What tools could AA leaders have used to increase their awareness of internal and external issues?...
What tools could AA leaders have used to increase their awareness of internal and external issues? ???ALASKA AIRLINES: NAVIGATING CHANGE In the autumn of 2007, Alaska Airlines executives adjourned at the end of a long and stressful day in the midst of a multi-day strategic planning session. Most headed outside to relax, unwind and enjoy a bonfire on the shore of Semiahmoo Spit, outside the meeting venue in Blaine, a seaport town in northwest Washington state. Meanwhile, several members of...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...