Question

What are the similarities and differences between miRNAs and siRNAs?

Answer 1

difference- 1.miRNA is a micro ribonucleic acid when siRNA is small interfering ribonucleic acid.
2.miRNA plays an important role in gene regulation while siRNa is known for gene silencing.
3.miRNA is a single-stranded but siRNA is double stranded.
4.Both miRNA and siRNA act on RNA interference (RNAi), but siRNA which is double stranded is best utilized for the cleaving of RNA when incorporated with RNA induced silencing complex (RISC).
5.miRNa binds with its target not very perfect while siRNA binds with its target very perfectly at a single site.
similarities-

siRNAs and miRNAs—act in both somatic and germline lineages ina very vast range of eukaryotic cells to regulate endogenous genes and to defend the genome from invasive nucleic acids.