Question

Which of the following proteins would be labeled in sealed ghosts?

A. Spectrin

B. Band 4.1

C. Band 3

D. Ankyrin

E. Glycophorin

Answer 1

Answer: Choices A, B, E

Explanation: Ghost cells are those enucleated cells which lose their nuclei at some stage of their life cycle. Red blood cells are called ghost cells as they lose their nuclei just after maturation. Similarly, prokaryotic cells such as bacteria also develop into ghost cells when they are devoid of their intracellular medium, i.e. all cytoplasm and only a cellular envelop remains. Thus, all the structures present in these eukaryotic and prokaryotic membranes would constitute to the sealed ghosts.

Since spectrin, Band 4.1 and glycophorin remain most abundant protein in red blood cells for transport of ions across the cell, they together will constitute to the sealed ghost and can be labelled as required.