a mutation that deleted a genes promoter would mean that
1) the gene could not be transcribed
2) the gene would be expressed continuously
3) the DNA could not be replicated at that site
4) the gene would have a frameshift mutation
Promoter is a region of DNA where transcription of a gene is
initiated. Promoters are a vital component of expression vectors
because they control the binding of RNA polymerase to DNA. RNA
polymerase transcribes DNA to mRNA which is ultimately translated
into a functional protein.Thus the promoter region controls when
and where in the organism your gene of interest is expressed.
Mutations in the promoter region results in the change in DNA
binding pattern of the transcription factor.Modulation of
transcription factors binding pattern lead to a change of
sequence-specific interaction between DNA-protein or
protein-protein in the transcription initiation complex.
Therefore the answer is 3 ie DNA could not be replicated at that
site.
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