Question

Which of the following conditions might suggest that a genomic DNA sequence contains a protein-coding gene?

Check the FOUR that apply.

Check the FOUR that apply.

Presence of upstream regulatory elements, such as promoters.

Conservation of similar sequences in other species.

Presence of downstream regulatory elements, such as translation termination sites.

Presence of open reading frame (ORF).

Presence of long repeated sequences.

Which of the following statements about proteomics are true?

Check the THREE that apply.

Check the THREE that apply.

There are many more types of proteins than genes.

Number of protein-coding genes is estimated by genome annotation.

Number of produced proteins can be estimated by electrophoresis, mass-spectrometry, and other techniques.

There are much less types of proteins than genes.

Answer 1

First question

Presence of upstream regulatory elements, such as promoters.

Conservation of similar sequences in other species.

Presence of downstream regulatory elements, such as translation termination sites.

Presence of open reading frame (ORF).

[long repeated sequences usually form the non coding parts of genome.]

Second question

There are many more types of proteins than genes.

Number of protein-coding genes is estimated by genome annotation.

Number of produced proteins can be estimated by electrophoresis, mass-spectrometry, and other techniques.

[from one gene a variety of proteins can be formed (alternate splicing).]