Question

What physical/chemical characteristic to consider when identifying the two closely-related proteins?

Answer 1

Physical characteristics to be considered to identify two closely related proteins

1. Number of domains

2. Number of subunits

3. Number of alpha helix, beta sheet, loop, beta barrels etc

Chemical characteristics to be considered to identify two closely related proteins

1. Sequence of amino acid

2. Interactions between intra-chain and inter-chain amino acids

3. Presence of different types of amino acids in primary structures of proteins such as acidic, basic, hydrophobic, hydrophilic, polar, non-Roman, aliphatic, aromatic amino acids.